Summary of recombinant biological molecules used Pichia pastoris for production

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The P. pastoris has also been established as a versatile cell factory for the production of thousands of biomolecules both on a laboratory and industrial scale.

ProductUsed strainUsed vectorUsage
Lycopene and __caroteneX_33pGAPZAFeed supplements
PlectasinX_33pPICZ_AAntibacterial peptide
Bovine lactoferrinKM71HpJ902Transferrin and antibacterial protein
Bovine IFN__GS115pPIC9KPrevention and therapy of viral diseases
ApidaecinSMD1168pPIC9KAntibacterial peptide
hPAB__GS115pPIC9KAntibacterial peptide
Tachyplesin IGS115pGAPZ_BAntibacterial peptide
Snakin_1GS11pPIC9Antimicrobial peptide
PAF102X_33pGAPZAAntifungal peptide
Pisum sativumÊdefensin 1GS115pPIC9KAntifungal peptide
Class I chitinaseKM71HpPICZ_AAntifungal peptide
Ch_penaeidinKM71HpPIC9KAntimicrobial peptide
HispidalinGS115pPICZ_AAntimicrobial peptide
Fowlicidin_2X_33pPICZ_AAntimicrobial peptide
Parasin IX_33pPICZ_AAntimicrobial peptide
CecropinA_thanatinX_33pPICZ_AAntimicrobial peptide
Type I collagenConnective tissue
Human serum albuminGS115pPIC9KMaintaining osmolarity and carrier in blood
LegumainX_33pPICZ_ALysosomal protease
Goat chymosinX_33pPICZ_AHydrolysis of __casein
Carrot antifreeze proteinGS115pPIC9KInhibition of gluten deterioration
ProinsulinSuperMan5pPICZ_ATreatment of diabetes mellitus
hIFN__X_33, GS115, KM71H, CBS7435pPICZ_, pPIC9, pPpT4aSCritical cytokine for innate and adaptive immunity
IL_1_GS115, SMD1168, X_33pPICZ_AProinflammatory cytokine
IL_3X_33pPICZ_AMultipotent hematopoietic cytokine
IL_11GS115pPINK_HCThrombopoietic growth factor
IL_15X_33pPICZ_ADifferentiation and proliferation of T, B, and NK cells
Cyanate hydrataseGS115pPICZ_ADetoxification of cyanate and cyanide
Human antiplatelet scFv antibodyX_33pPICZ_ATreatment of atherosclerosis
__AmylaseX_33pPICZ_AStarch saccharification
Human epidermal growth factorGS115pPIC9KGeneration of new epithelial and endothelial cells
BromelainKM71HpPICZ_AOedematous swellings
Keratinocyte growth factorX_33pPICZ_AEpithelialization_phase of wound healing
DM64X_33pPICZ_AAnti_myotoxic
TrypsinGS115pPIC9KHydrolysis of proteins in the digestive system
Human sialyltransferaseKM71HpPICZ_BPharmacological uses
TransglutaminaseGS115pPIC9KRestructured meat products
StreptokinaseX_33pPICZ_AThrombolytic medication
StaphylokinaseGS115, KM71HpPICZ_AThrombolytic medication
TFPR1X_33pPICZ_AAdjuvant

Table:Summary Of Recombinant Biological Molecules Used Pichia Pastoris For Production

Ref: Pichia pastoris: A highly successful expression system for optimal synthesis of heterologous proteins

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